Sequential hyperglycemic-euglycemic clamp to assess b-cell and peripheral tissue: studies in female athletes
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چکیده
ALICE S. RYAN,1 DENIS C. MULLER,2 AND DARIUSH ELAHI1 1 Division of Gerontology, Department of Medicine, University of Maryland School of Medicine, and Geriatrics Service/Geriatric Research, Education, and Clinical Center, Baltimore Veterans Affairs Medical Center, Baltimore 21201; and 2Laboratory of Clinical Physiology, Gerontology Research Center, National Institute on Aging, Baltimore, Maryland 21224
منابع مشابه
Sequential hyperglycemic-euglycemic clamp to assess beta-cell and peripheral tissue: studies in female athletes.
Insulin secretion and rate of utilization (R(d)) of glucose were tested during a newly developed sequential clamp in 42 highly trained female athletes (A; 18-69 yr old) and 14 sedentary control women (C; 18--50 yr old; body mass index <25 kg/m(2)). The A women were categorized into four age groups: 18--29, 30--39, 40--49, and 50--69 yr old. The C women were also grouped by age (18--29 and 40--5...
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OBJECTIVE To compare β-cell function relative to insulin sensitivity, disposition index (DI), calculated from two clamps (2cDI, insulin sensitivity from the hyperinsulinemic-euglycemic clamp and first-phase insulin from the hyperglycemic clamp) with the DI calculated from the hyperglycemic clamp alone (hcDI). RESEARCH DESIGN AND METHODS Complete data from hyperglycemic and hyperinsulinemic-eu...
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تاریخ انتشار 2001